17:30 - 19:00

Symposium 1

Early Career Physiologists

Chair: Dr. Alberto Sanchez Aguilera-Lopez – University Complutense of Madrid (Spain)

Room 1 (Paraninfo)

Dr. Andreas Breenfeldt – Aarhus University (Denmark)

Title: The performance-enhancing effects of blood doping and detection possibilities in trained males and females

Dr. Agustin Hidalgo – Columbia University (USA)

Title: Guanylate Kinase 1 Deficiency: A Novel and Potentially Treatable Mitochondrial DNA Depletion/Deletions Disease

Dr. Pamela Swiatlowska – Imperial College London (UK)

Title: Hypertensive Pressure Mechanosensing Triggers Transdifferentiation of Vascular Smooth Muscle Cells to Foam Cells

Dr. Alberto Sanchez Aguilera-Lopez – University Complutense of Madrid (Spain)

Title: Cortical and hippocampal rhythmpathies in experimental models of brain metastasis evaluated with supervised learning tools

Dr. Valentina Sica – University Pompeu Fabra (Spain)

Title: Circadian rhythms in muscle stem cells

Time

Session

Speakers

9:00 – 9:45

Keynote Lecture 1

Room 1 (Paraninfo)

Prof. Juan Iovanna – Marseille Cancer Research Center (France)

Title: The cellular stress response as an efficient therapeutic target for treating pancreatic cancer

9:00 – 9:45

Keynote Lecture 2

Room 2 (Medicine assembly hall)

Prof. Christian Aalkjær – Aarhus University (Denmark)

Title: Transport of negative ions over cell membranes – a positive story

10:00 - 11:30

Symposium 2

Improving Public Understanding of the Use of Animals for Scientific Purposes

Chair: Mr. Kirk Leech – European Animal Research Association (EARA)

Room 1 (Paraninfo)

Mr. Kirk Leech – Executive Director European Animal Research Association (EARA)

Title: Animal Research: Time to Talk

Dr. Monique Havermans – Coordinator Transparency Agreement on Animal Research (Netherlands)

Title: Transparency in Animal Research in the Netherlands: Achievements and Challenges

Dr. Javier Guillen – Senior Director for Europe & Latin America, AAALAC International (Spain)

Title: The Spanish Transparency Agreement: An Example of Success

10:00 - 11:30

Symposium 3

Regulation of synaptic homeostasis in health and disease.

Chair: Dr. Anna Fassio – University of Genoa (Italy)

Room 2 (Medicine assembly hall)

Dr. Mike Cousin – University of Edinburgh (UK)

Title: Dynamin-1 function in presynaptic physiology and dysfunction in epileptic encephalopathy

Dr. Marta Orlando – Charité – Universitätsmedizin Berlin (Germany)

Title: Role of Synapsin in Hippocampal Mossy Fiber Presynaptic Plasticity

Dr. Erica Tagliatti – IRCCs Humanitas Research Hospital (Italy)

Title: Microglial TREM2 receptor shapes CA1 metabolism and glutamatergic synapses during development

Dr. Anna Fassio – University of Genoa (Italy)

Title: The epilepsy gene TBC1D24 regulates intracellular pH homeostasis in neurons ad synapse

10:00 - 11:30

Symposium 4

Are we programmed for cardiometabolic disease?

Chairs: Dr Amanda Sferruzzi-Perri – University of Cambridge (UK); Dr Silvia Arribas – Autonomous University of Madrid  (Spain)

Room 3 (Medicine hall)

Dr. Emilio A. Herrera – University of Chile (Chile)

Title: Deciphering the gasotransmitters´ function on the cardiovascular programming induced by intrauterine chronic hypoxia

Dr. Carmen Diniz – University of Porto (Portugal)

Title: Nuclear angiotensin receptors and the fetal programming of hypertension

Dr. Jonas Zaugg – University of Cambridge (UK)

Title: Effect of parental obesity on placental nutrient transport in relation to fetal developmental outcomes

Dr. David Ramiro-Cortijo – Autonomous University of Madrid (Spain)

12:00 – 13:30

Opening Ceremony

Plenary Lecture 

Room 1 (Paraninfo)

Prof. Rodrigo Quian Quiroga – Hospital del Mar Research Institute (Spain)

Title: A unique coding of memories in the human hippocampus

15:00 – 17:00

Oral Communications 1

Endocrinology, metabolism and nutrition

Room 1 (Paraninfo)

15:00     O1          Twenty-four weeks of moderate-intensity, but not vigorous-intensity, exercise training modulates the plasma lipidome in young adults: a secondary analysis from the ACTIBATE randomized controlled trial. Lucas Jurado Fasoli

15:15     O2          Role of lingual CD36 in fat oro-sensory perception: tongue-brain axis. Aziz Hichami

15:30     O3          Impact of Caloric Restriction on Beta Cell Function in Diet-Induced Type 2 Diabetic Mice. Jurij Dolenšek

15:45     O4          Postnatal exposure to emerging endocrine disruptor chemical present a risk factor for gastrointestinal disorders in mice. Raja Rezg

16:00     O5          Penile Endothelial Dysfunction and Impaired Redox Metabolism and Mitochondrial Bioenergetics in Diet-Induced Obesity: Compensatory Role of H2O2. Alfonso Gómez del Val

16:15     O6          Alteration of placental and umbilical cord plasma oxidative stress in maternal obesity. Sophida Phuthong

16:30     O7          Gut-brain axis modulation prevents diet-induced cognitive dysfunction, inflammation and oxidative stress in rat brain. Luisa Cigliano

16:45     O8          Diet-induced impairment of skeletal muscle and adipose tissue metabolic homeostasis and its prevention by probiotic administration. Arianna Mazzoli

15:00 – 17:00

Oral Communications 2

Neuroscience and neurophysiology

Room 2 (Medicine assembly hall)

15:00     O9          A specific matrisome composition drives a regeneration program in peripheral nerve repair. Marina Damato

15:15     O10       Cognitive Impact of Central Auditory Processing on Listening Effort: Insights from a Simultaneous EEG and Pupillometry Study. Samet KILIÇ

15:30     O11       Assessment of auditory and visual attention in young adults according to gender differences. Kerem Ersin

15:45     O12       Antioxidant effects of docosahexaenoic acid in an experimental model of multiple sclerosis. Ana Muñoz Jurado

16:00     O13       Human neural stem cells communicate with each other through tunneling nanotubes, exchanging organelles and self-renewal signals. Francesco Pisani

16:15     O14       Altered basal phosphorylation levels of synaptic enzymes and glutamate ionotropic receptors across life: influence on hippocampal LTP. Diana Cunha-Reis

16:30     O15       Expression of guanylate cyclase C and uroguanylin in the brain is regulated by feeding. Aleksandra Dugandžić

16:45     O16       Calcineurin B1 deletion in astrocytes rescues memory loss and histopathology in Alzheimer's disease mouse models. Laura Paola Ferilde Tapella

17:15 - 18:45

Symposium 5

Physiology education in health sciences

SPFis - the Portuguese Society of Physiology

Chair: Prof Vicente Martinez Perea - Autonomous University of Barcelona (Spain)

Room 1 (Paraninfo)

Dr. Erica Wehrwein – Michigan State University (USA)

Title: Current trends to improve physiology teaching and learning in the USA (ONLINE lecture)

Dr. Jorge Ascenção Oliveira – SPFis, University of Porto (Portugal)

Title: Integrating Metacognition in Physiology Education

Dr. Joaquin Garcia-Estañ – University of Murcia (Spain)

Title: Physiology Medical Education in Health Sciences

Dr. Luis Monteiro Rodrigues – SPFis, University Lusofona (Portugal)

Title: Current state of Physiology (teaching and research) in the post-Bologna Europe – the case study of Portugal

Dr. Abdullateef I. Alagbonsi – University of Rwanda (Rwanda)

Title: The Physiology Curriculum for African Universities (PhysioCAFUN): a huge step to strengthen Physiology Education in Africa

17:15 - 18:45

Symposium 6

Orai calcium channels: regulation and function

Chair: Dr. Tarik Smani – Institute of Biomedicine of Seville (Spain)

Room 2 (Medicine assembly hall)

Dr. Rainer Schindl – Medical University of Graz (Austria)

Title: Activation mechanism of store-operated calcium channels: a computer simulation and live cell approach

Dr. Juan A. Rosado – University of Extremadura (Spain)

Title: Modulation of the protein content of Orai1α and Orai1β by STIM

Dr. Isabel Galeano-Otero – University of Bordeaux (France)

Title: Sulconazole prevents T-cell exhaustion and promotes cancer cell malignant phenotype repression by attenuation of NF-κB and calcium signaling

Dr. Debora Falcon – University of Seville (Spain)

Title: Role of Ca2+-sensitive adenylyl cyclase 8 in the overexpression of Orai1 after myocardial infarction

17:15 - 18:45

Symposium 7

Understanding the Physiology of the Blood-Brain Barrier: from Molecular Mechanisms to Modulation Strategies

Chairs: Dr. Luca Maragliano – Polytechnic University of Marche (Italy); Dr. Valentina Castagnola – Italian Institute of Tecnology  (Italy)

 Room 3 (Medicine hall)

Dr. Jörg Piontek – Charité – Universitätsmedizin Berlin (Germany)

Title: Comparison of TJ strands architecture in epithelia and BBB endothelium

Dr. Luca Maragliano – Polytechnic University of Marche (Italy)

Title: Enhancing the BBB permeability using structure-based peptide design

Dr. Valentina Castagnola – Italian Institute of Technology (Italy)

Title: Paracellular and transcellular approaches to overcome the BBB

Dr. Joe Forth – University of Liverpool (UK)

Time

Session

Speakers

9:00 – 10:30

Symposium 8

Muscle mitochondria: Beyond ATP production

Chair: Prof. Jesus R Huertas – University of Granada (Spain); Dr. Rafael A Casuso – University of Loyola (Spain)

Room 1 (Paraninfo)

Dr. Rafael A Casuso – University Loyola (Spain)

Title: Electron transport chain dynamics during exercise.

Dr. Laura Formentini – Autonomous University of Madrid, Centre for Molecular Biology Severo Ochoa (CBM, CSIC-UAM) (Spain)

Title: Skeletal muscle OXPHOS system in health and disease

Dr. Sara Cogliati – Autonomous University of Madrid, Centre for Molecular Biology Severo Ochoa (CBM, CSIC-UAM) (Spain)

Title: Sex differences in mitochondrial functions

Dr. Carsten Lundby – University of Southern Denmark (Denmark)

Title: Skeletal muscle mitochondria in extreme environments

9:00 – 10:30

Symposium 9

Integrative learning: factors and approaches for improved academic performance.

Chair: Dr. Beatriz Gal – University San Pablo CEU (Spain)

Room 2 (Medicine assembly hall)

Dr. Cayetana Ruiz Zaldibar – University Camilo José Cela (Spain)

Title: Relationship between sleep quality in nursing students and their academic performance: results of a randomized controlled trial

Prof. Dr. Cheng Hwee Ming – University of Malaya (Malaysia)

Title: Question-based learning in Physiology teaching

Dr. Isabel Sánchez-Vera – University San Pablo CEU (Spain)

Title: Enhancing medical education through competency-based learning

Dra. Marta Lesmes Celorrio – European University of Madrid (Spain)

Title: Applying knowledge in context: role of integrated laboratory classes on learning physiology

10:45 - 11:30

Keynote Lecture 3

Room 1 (Paraninfo)

Dr. Elena Osto – Medical University of Graz (Austria)

Title: Vascular function in cardiometabolic disorders

10:45 - 11:30

Industry-sponsored lecture

Room 2 (Medicine assembly hall)

Dr. Juan Ignacio Cacho Aparicio – Health Tech BioActives (Spain)

Title: Effects of 2S-Hesperidin on physical performance

12:00 - 13:30

Oral Communications 3

Cardiovascular physiology

Room 1 (Paraninfo)

12:00     O17       Calcium physiology and pathophysiology in the heart of zebrafish larvae with fluorescent biosensors. Juan Llopis Borras

12:15     O18       The effect of acute hyperglycemia on microvascular reactivity challenged by iontophoresis of acetylcholine. Lana Kralj

12:30     O19       Sex differences in aging-related miR-149-5p modulation of the angiogenesis pathway in experimental acute myocardial infarction. Cristina Rosales Ariza

12:45     O20       Alanine mutation of the targeting subunit of the myosin-light-chain-phosphatase, MYPT1 prevents development of hypercontractile phenotype of murine interlobar arteries. Lubomir Todorov Lubomirov

13:00     O21       Exercise-induced alterations of the murine heart during doxorubicin treatment of breast cancer. Tytti-Maria Uurasmaa

13:15     O22       Role of lipoma-preferred partner in the phenotype control of vascular smooth muscle cells. Markus Hecker

12:00 - 13:30

Oral Communications 4

Miscellaneous

Room 2 (Medicine assembly hall)

12:00     O23       Effect of moderate hypobaric hypoxia on both heart and skeletal muscle during the first 24 hours of exposure. Jerónimo Aragón Vela

12:15     O24       Lauric acid enhances endothelium-independent relaxation in the corpus cavernosum of streptozotocin-induced diabetic male Wistar rats. Makinde Olubiyi

12:30     O25       Fresh or fatigued assessment of VO2max? Preliminary observations on the durability of competitive, national-level male triathletes. Marco Morrone

12:45     O26       Maximal myocardial blood flow and minimal vascular resistance in untrained and endurance-trained men. Ilkka Heinonen

13:00     O27       Accumulation of oral and inhaled nano and microplastics in various organs of male and female mice disrupts memory and leukocyte trafficking. Mustafa Sevim

13:15     O28       Evolutionary-conserved temperature dependency leads to loss of protein O-GlcNAc in mammalian hypothermia. Janne Purhonen

15:00 - 16:30

Symposium 10

New in silico and in vitro approach methodologies for designing physiologically relevant models of human tissues.

Chairs: Prof Arti Ahluwalia – University of Pisa (Italy); Dr Elena Grasselli – University of Genoa (Italy)

Room 1 (Paraninfo)

Prof. Arti Ahluwalia – University of Pisa (Italy)

Title: Lab on a Laptop

Dr Elena Grasselli – University of Genoa (Italy)

Title: Skin Homeostasis and Sustainable Cosmetic Products

Dr. Laureano E. Carpio – ProtoQSAR SL (Spain)

Title: Quantitative structure-activity relationships in pharmacokinetics: predicting human tissue permeability for drug optimization

Dr. Giulia De Negri Atanasio – University of Genoa (Italy)

Title: The endocrine disruptor and their impact on human physiology

15:00 - 16:30

Symposium 11

Extracellular matrix in health and disease.

Chair: Prof. Eva Sykova – Institute of Neuroimmunology, Slovak Academy of Sciences Bratislava (Slovakia)

Room 2 (Medicine assembly hall)

Prof. Eva Sykova – Institute of Neuroimmunology, Slovak Academy of Sciences Bratislava (Slovakia)

Title: Astrocytes and extracellular matrix in extrasynaptic transmission and neuroplasticity

Prof. Dr. Juan Nacher – University of Valencia (Spain)

Title: Dysregulation of ECM in psychiatric disorders: Impact on the connectivity of inhibitory networks

Dr. Federico N. Soria – Achucarro Basque Center for Neuroscience (Spain)

Title: The structure and distribution of the extracellular matrix affect the movement and migration of brain cells

Dr. Carla Cangalaya – German Center for Neurodegenerative Diseases (Germany)

Title: Integrity of neural extracellular matrix is required for microglia-mediated synaptic remodeling

15:00 - 16:30

Symposium 12

Environmental Factors in the Pathophysiology of Cardiovascular Diseases

Chairs: Prof. Devendra K. Agrawal – Western  University of Health Sciences (California, USA); Prof. Dragan M. Djuric – University of Belgrade (Serbia)

Room 3 (Medicine hall)

Prof. Devendra K. Agrawal – Western University of Health Sciences (California, USA)

Title: Pathophysiological effects of the environmental factors and treatment strategies in cardiovascular diseases

Prof. Dragan M. Djuric – University of Belgrade (Serbia)

Title: Homocysteine: a potential biomarker of environmental health risk and links to cardiovascular pathogenesis

Prof. Ildiko Bock-Marquette – University of Pecs (Hungary)

Title: Novel approaches in reversing environmental stress initiated pathological processes to accelerate organ repair - the power of small molecules

Dr. Zorislava Bajić – University of Banja Luka (Bosnia and Herzegovina)

Title: Isoprenaline model as stress induced myocardial injury

17:00 - 18:30

Closing Ceremony

Plenary Lecture 

Room 1 (Paraninfo)

"RISING STAR AWARD 2024"

Dr. Borja Martinez Téllez – University of Almeria (Spain)

Title: Deciphering the Molecular and Secretory Functions of a Novel and Unique Brown Adipose Tissue Depot in Women